Anti-CD44 (human/mouse) PE-Cy5 clone IM7

Code: MABF425 D2-231

Application

This rat monoclonal antibody Anti-CD44 (human/mouse), PE-Cy5, clone IM7 validated for use in Western Blottting, IP, IHC & Flow Cytometry for the detection of CD44...


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Your Price
€315.00 EACH
€387.45 inc. VAT

Application

This rat monoclonal antibody Anti-CD44 (human/mouse), PE-Cy5, clone IM7 validated for use in Western Blottting, IP, IHC & Flow Cytometry for the detection of CD44. This CD44 Antibody has been tested in Human and Mouse.

General description

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, throµgh which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141). It has been reported to be cross-reactive with many non-human species including Baboon, Chimpanzee, Cynomolgus, Rhesus, Horse, Cow, Pig, Dog and Cat CD44.

Quality

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.125 µg of this antibody detected CD44 in one million C57Bl/6 splenocytes.

antibody formpurified antibody
antibody product typeprimary antibodies
biological sourcerat
cloneIM7, monoclonal
concentration0.2 mg/mL
conjugatePE-Cy5
Gene Informationhuman ... CD44(960)mouse ... Cd44(12505)
isotypeIgG2bκ
Quality Level100
shipped inwet ice
species reactivitymouse, human
technique(s)western blot: suitable, flow cytometry: suitable, immunoprecipitation (IP): suitable, immunohistochemistry: suitable
UniProt accession no.P15379
This product has met the following criteria to qualify for the following awards:



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